...the who's who,
and the what's what 
of the space industry

Space Careers

news Space News

Search News Archive

Title

Article text

Keyword

  • Home
  • News
  • Murine study suggests cosmic radiation in outer space may affect long-term cognition

Murine study suggests cosmic radiation in outer space may affect long-term cognition

Written by  Wednesday, 25 September 2024 15:40
Write a comment
space
Credit: Pixabay/CC0 Public Domain

During missions into outer space, galactic cosmic radiation (GCR) will penetrate current spacecraft shielding and thus pose a significant risk to human health.

Previous studies have shown that GCR can cause short-term cognitive deficits in male rodents. Now a study published in the Journal of Neurochemistry reveals that GCR exposure can also cause long-lasting learning deficits in female rodents.

The impact of GCR on cognition was lessened when mice were fed an antioxidant and anti-inflammatory compound called CDDO-EA.

Beyond its immediate implications for , the findings contribute to a broader understanding of radiation's long-term impact on cognitive health.

"Our study lays the groundwork for future causal delineation of how the brain responds to complex GCR exposure and how these brain adaptations result in altered behaviors," said co-corresponding author Sanghee Yun, Ph.D., of the Children's Hospital of Philadelphia Research Institute and the University of Pennsylvania Perelman School of Medicine.

More information: S. Yun, F.C. Kiffer, et al. The longitudinal behavioral effects of acute exposure to galactic cosmic radiation in female C57BL/6J mice: implications for deep space missions, female crews, and potential antioxidant countermeasures, Journal of Neurochemistry (2024).

DOI: 10.1111/jnc.16225

Journal information:Journal of Neurochemistry

Provided by Wiley

Citation: Murine study suggests cosmic radiation in outer space may affect long-term cognition (2024, September 25) retrieved 25 September 2024 from https://phys.org/news/2024-09-murine-cosmic-outer-space-affect.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Read more from original source...

You must login to post a comment.
Loading comment... The comment will be refreshed after 00:00.

Be the first to comment.

Interested in Space?

Hit the buttons below to follow us...