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Expiring medications could pose challenge on long space missions

Medications used by astronauts on the International Space Station might not be good enough for a three-year journey to Mars. A new study led by Duke Health shows that over half of the medicines stocked in space—staples such as pain relievers, antibiotics, allergy medicines, and sleep aids—would expire before astronauts could return to Earth.
Astronauts could end up relying on ineffective or even harmful drugs, according to the study appearing July 23 in npj Microgravity.
"It doesn't necessarily mean the medicines won't work, but in the same way you shouldn't take expired medications you have lying around at home, space exploration agencies will need to plan on expired medications being less effective," said senior study author Daniel Buckland, M.D., Ph.D., an assistant professor of emergency medicine at Duke University School of Medicine and an aerospace medicine researcher.
Expired medications can lose their strength by a little—or a lot. The actual stability and potency of medications in space compared to Earth remain largely unknown. The harsh space environment, including radiation, could reduce the effectiveness of medications.
Buckland and co-author Thomas E.
NASA's Artemis II moon mission rocket core stage on way to Kennedy Space Center

The biggest piece of the puzzle to send humans on a trip around the moon for the first time in more than half a century is on its way to Kennedy Space Center.
The Boeing-built core stage of NASA's Space Launch System rocket was loaded onto NASA's Pegasus barge from the Michoud Assembly Facility in New Orleans, and is now taking the 900-mile trip to Florida.
The flight hardware that includes the four RS-25 engines made by Aerojet Rocketdyne from the space shuttle era will then be taken to the Vehicle Assembly Building where it will be turned upright standing 212 feet tall. It will be married to other components of the SLS rocket including two solid rocket boosters from Northrop Grumman that when combined produce 8.8 million pounds of thrust on liftoff.
The next flight is Artemis II, which is targeting launch from KSC's Launch Pad 39-B no earlier than September 2025. That mission will take NASA astronauts Reid Wiseman, Victor Glover and Christina Koch along with Canadian astronaut Jeremy Hansen on a trip out to the moon and back aboard the Orion spacecraft built by Lockheed Martin.