Pascale Lefebure graduated from Master of Biology in 2009. She began her career as an R&D engineer for an ecological solutions company, Metabolium, to automate the growth of micro algae with Tecan robotic system. From 2010 to 2015, she has worked as a scientific expert for the French Ministry of Defense and French Ministry of Interior. She has conducted numerous studies on emerging technologies. In 2015, she followed her husband in America. As part of a professional reorientation in space field, she is involved in a one-year advanced Mastere's degree in Aerospace project management with the Higher Institute of Aeronautics and Space ISAE Supaero and joined Kayser Italia a payload developer for life sciences experimentation in Space. Since 2020, she work for SIGMA-VISION.COM on various aerospace project, as Legends-lab.space (space education) or Air Catalogne. From 2013 to today, she was speaker on emerging technologies in many conferences.